TBHP-mediated highly efficient dehydrogenative cross-oxidative coupling of methylarenes with acetanilides

• Cui Chen,
• Weibing Liu and
• Peng Zhou

Beilstein J. Org. Chem. 2016, 12, 2250–2255, doi:10.3762/bjoc.12.217

• C–N bonds. Besides, this conversion is an important complement to the conventional C–N forming strategies. Keywords: dehydrogenative cross oxidative coupling; methyl arenes; N-arylbenzamides; TBHP; Introduction Recently, amides have attracted more and more attention due to their extensive

• , entries 2, 3, 5, and 9). To further extend the adaptability of this transformation, other methyl arenes were also checked under the standard conditions. Pleasingly, m-xylene and p-xylene afforded the desired product 3 successfully, but in lower yields (Table 2, entries 10 and 11). In the same manner, we